Endocervical Curettage, Colposcopy
The pre- and postoperative value of endocervical curettage in the detection of cervical intraepithelial neoplasia and invasive cervical cancer.Fine BA, Feinstein GI, Sabella V. Gynecol Oncol. 1998 Oct;71(1):46-9.
Endocervical curettage helpful in preoperative evaluation of patients who required conization, but not in follow-up care in patients with positive margins. 391 patients studied.
Detection of cervical cancer and its precursors by endocervical curettage in 13,115 colposcopically guided biopsy examinations.Gage JC, Duggan MA, Nation JG, Gao S, Castle PE. Am J Obstet Gynecol. 2010 Nov;203(5):481.e1-9. Epub 2010 Aug 30.
Endocervical curettage detected 5.4% of CIN 2+ otherwise missed by cervical biopsy in 2443 colposcopic cases studied. It was especially helpful in women 46 years of age or older. Otherwise, the yield of CIN 2+ in over 13,000 cases was just over 1%.
The value of endocervical curettage as part of the standard colposcopic evaluation.Granai CO, Jelen I, Louis F, Kawada CY, Curry SL. J Reprod Med. 1985 May;30(5):373-5.
In 278 colposcopic exams studied, the abnormal ECC rate in satisfactory colposcopy was 11.5%. in 22% of cases where biopsy and ECC were performed, the ECC was of higher grade.
Of 374 women with ASCUS or LSIL Pap smears undergoing colposcopy; of those with a visible lesion at colposcopy, all underwent biopsy and ECC. There were 16 cases of CIN 2+ on ECC (4.3%), but only just over 1% had solely endocervical high grade CIN.
Pooled analysis on the necessity of random 4-quadrant cervical biopsies and endocervical curettage in women with positive screening but negative colposcopy.
Medicine (Baltimore). 2017 Apr;96(17):e6689. doi: 10.1097/MD.0000000000006689
Lack of Agreement Between Endocervical Brush and Endocervical Curettage in Women Undergoing Repeat Endocervical Sampling.
Doo DW, Stickrath EH, Mazzoni SE, Alston MJ. J Low Genit Tract Dis. 2016 Oct;20(4):296-9.
The study sought to evaluate agreement between an abnormal endocervical brush (ECB) collected at the time of colposcopy and subsequent endocervicalcurettage (ECC). Seventy nine cases were included for comparison. Only 4 of 54 women with low-grade ECB correlated with the ECC pathology grade. 47 of 54 cases were showed normal histology (87% overcall). Only 4 or 25 women with high-grade ECB correlated with the histological findings on ECC. Twenty of 25 patients had normal histology (80% overcall rate).
Utility of random cervical biopsy and endocervical curettage in a low-risk population. Pretorius RG, Belinson JL, Azizi F, Peterson PC, Belinson S.
J Low Genit Tract Dis. 2012 Oct;16(4):333-8.
Of 4932 colposcopies performed 5.1% of CIN 3+ was diagnosed on ECC only. The authors state that colposcopiy in women over 25 should include ECC.