Skip to main content

SpiraBrush CX

SpiraBrush CX®

Histologics is excited to offer the SpiraBrush CX®. SpiraBrush CX® is a twisted stiffer nylon bristle brush that removes trans-epithelial samples of the ectocervix.  The tip of the SpiraBrush contains tissue trapped in between the bristles can be snapped free and placed in fixative for lab transport. 
SpiraBrush CX® users should also be aware that Histologics markets the FDA-compliant and patented Kylon® fabric-based brush technology for exocervical tissue biopsy sampling.  These Kylon® based devices for ectocervical and endocervical sampling also have the FDA registered benefit of trapping and retaining the tissue removed, resulting in a research proven consistent, abundant, reliable, and diagnostic sample.

The Kylon® based ectocervical SoftBiopsy® device provides a minimally invasive approach with greater value (reprints of fabric based colposcopy research evidence is available upon request). The list price of SoftBiopsy® is lower than SpiraBrush. Pathology labs that have processed both SpiraBrush CX® and SoftBiopsy® samples report to Histologics that the fabric-based specimens are of higher diagnostic yield.

Many labs nation-wide have received stiff bristle brush or Kylon® trapped biopsy specimens, and some buy in volume and provide superior pricing to their colposcopist clients. Thus, the colposcopist could reach out to their lab, and if fabric-based biopsy is not yet available, encourage the lab to contact Histologics to purchase in volume and pass along savings based on their purchase advantages over smaller or group clinical practices.  

Furthermore, many SpiraBrush users have requested a minimally invasive brush for endocervical curettage (ECC).  The fabric-based Soft-ECC® is similarly priced, comes in two sizes (regular and small), and is the only minimally invasive simultaneous biopsy device combined with a tissue trap system available for this use.  The 2014 ASCCP Meeting Award winning research on fabric ECC showed a simple single insertion/ rotation/withdrawal method with simultaneous tissue trapping, increases the diagnostic specimen yield that returns to the laboratory, nearly eliminating insufficient samples, while remaining a very gentle approach to ECC that patients appreciate.

We welcome questions and value your business.

Thank you.

Neal M. Lonky, MD, MPH
Inventor and Founder; Histologics LLC
Research Publications related to the use of Spirabrush CX -
 2004 Oct;8(4):276-9.

Transepithelial sampling of the uterine ectocervix with a stiff-bristled, spiral-shaped brush.

 2002 Dec;100(6):1276-84.

A stiff bristled, spiral-shaped ectocervical brush: a device for transepithelial tissue biopsy.


Spiral brush cervical biopsy experience in a community clinic.

 2017 Oct;21(4):304-306. doi: 10.1097/LGT.0000000000000324.

Comparison of Tissue Yield Using Frictional Fabric Brush Versus Sharp Curettage For Endocervical Curettage.

Author information

1Family Planning Services Department of Obstetrics & Gynecology, University of California, Riverside Riverside, CA; 2Aurora Diagnostics Bernhardt Laboratories, Jacksonville, FL; 3Aurora Diagnostics, Las Vegas, NV.